When picking or editing a gaming or anime PFP, focus on a clear silhouette and...

https://dlf-ne.org/why-do-subtle-expressions-fail-in-small-profile-icons/

When picking or editing a gaming or anime PFP, focus on a clear silhouette and crop tightly around the face to keep it recognizable. Use a simple background with good contrast so the image doesn’t get lost when shrunk